Sandip Kumar Rajak
Present study shows the correlation of activity of as many as 13 Anti-bacterial (containing benzimidazole and beta-lactam moiety) drugs in terms of global reactivity descriptors under paradigm of QSPR/QSAR study. Investigation of antimicrobial activity of the compounds was done by using Gram- positive (S. aureus, S. mutans and B. subtilis) bacteria. The global descriptors nicely correlate the variation of activity with structures of the drug molecules