N.Chitra
The effect of probiotics in systemic health is well documented. There are several advantages using of probiotics , but in some persons it carries the risk of causing bacteremia and sepsis. Probiotic treatment is adviced for the prevention and treatment of a number of diseases, and there is strong evidence for their efficacy. Probiotics are now widely used in many countries . Because of the increasingly widespread use of probiotics, a thorough understanding of their adverse effects and benefits is necessary. In this study the safety of probiotics and risks of probiotic use is discussed. Although probiotics have a good overall safety record, they should however be used with caution in certain patient groups such as premature infants , patients with immune deficiency and patients who undergo dental manipulations or dental surgical procedures.