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Hypolipidemic effect of Moringa oleifera leaf extract in cadmium exposed rats

Pratik Kumar Chatterjee, Vinodini N.A, Anwar Amemarsoofi, Nayanatara AK, Sheila R. Pai, Suman VB

Cadmium, an extremely toxic metal leads to a large number of health conditions like, diabetes, cancer, cardiovascular diseases etc., Studies have shown that exposure to cadmium causes hyperlipidaemia & also hypercholesterolemia. Moringa oleifera, a ‘Miracle Tree’, is having a wide range of medicinal uses like, anti-oxidant, hepato-protective, cholesterol lowering actions, etc., with a high nutritional value. Therefore, the present study was designed to elucidate the effect of aqueous leaf extract of Moringa oleifera on lipid profile in cadmium exposed adult Wistar rats. Twenty four male Wistar Albino rats were divided into four groups. Pre-treatment with Moringa leaf extract in cadmium exposed rats showed a significant decrease in the levels total cholesterol, triglyceride, HDL, LDL & VLDL as compared to the untreated control group. Therefore, the present study suggests that pre-treatment with Moringa oleifera leaf extract has a positive effect in lowering the lipid profile in cadmium exposed rats.