Abstrait

Antimicrobial Activities and Bioactive Metabolites from Marine Algae Valoniopsis pachynema and Sargassum swartzii

Devaraj Isaac Dhinakaran, Ravichandran Rajalakshmi, Thangavel Sivakumar, Solomon Jeeva

Marine macroalgae act as the prominent source of marine natural products. The presence study was carried out to investigate the potential bioactive metabolites in the marine algae Valoniopsis pachynema and Sargassum swartzii and to detect its antimicrobial properties. The bioactive metabolites were screened using the phytochemical analysis, UV, FTIR and HPLC analysis. Antibacterial activity was tested against five different strains such as Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, klebsiella pnuemoniae and Bacillus subtilis by agar disc diffusion method. Antifungal activity was detected against various organisms such as the Aspergillus niger and Penicillin notatum using agar well diffusion method. The presence of bioactive metabolites such as terpenoids, flavonoids was detected. These results indicate that Valoniopsis pachynema and Sargassum swartzii could be used for the development of marine derived drugs.